Recombinant parathyroid hormone for hypoparathyroidism in children: a narrative review
نویسندگان
چکیده
منابع مشابه
Recombinant parathyroid hormone therapy for severe neonatal hypoparathyroidism.
ypoparathyroidism-retardation-dysmorphism (HRD) syndrome (OMIM 241410), also known as SanjadSakati syndrome, is a rare autosomal recessive disorder characterized by hypoparathyroidism, growth failure, developmental delay, and characteristic facies. We describe the effective short-term use (tapered over 12 days) of recombinant parathyroid hormone (PTH) (teriparatide) in an unusual genetic condit...
متن کاملParathyroid hormone replacement in hypoparathyroidism
Hypoparathyroidism results from insufficient parathyroid hormone (PTH) to maintain normal serum levels of calcium and phosphate. Unlike most endocrine deficiency disorders, the current standard of treatment is not replacement with PTH but supplementation with calcium and vitamin D. Normal physiology cannot be fully restored with calcium and vitamin D, and long-term complications of this treatme...
متن کاملHypoparathyroidism: Replacement Therapy with Parathyroid Hormone
Hypoparathyroidism (HypoPT) is characterized by low serum calcium levels caused by an insufficient secretion of parathyroid hormone (PTH). Despite normalization of serum calcium levels by treatment with activated vitamin D analogues and calcium supplementation, patients are suffering from impaired quality of life (QoL) and are at increased risk of a number of comorbidities. Thus, despite normal...
متن کاملParathyroid Hormone Replacement Therapy in Hypoparathyroidism: A Meta-Analysis
▼ This study investigated the effect of human parathyroid hormone replacement therapy on specific disease-related outcomes in patients with hypoparathyroidism. Medline, Cochrane, EMBASE, and Google Scholar databases were searched until January 13, 2015 for randomized trials using the following search terms: hypoparathyroidism, parathyroid hormone/PTH, and hormone replacement therapy. Five rando...
متن کاملParathyroid Hormone Replacement Therapy in Hypoparathyroidism: A Meta-Analysis.
This study investigated the effect of human parathyroid hormone replacement therapy on specific disease-related outcomes in patients with hypoparathyroidism. Medline, Cochrane, EMBASE, and Google Scholar databases were searched until January 13, 2015 for randomized trials using the following search terms: hypoparathyroidism, parathyroid hormone/PTH, and hormone replacement therapy. Five randomi...
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ژورنال
عنوان ژورنال: Pediatric Endocrinology Diabetes and Metabolism
سال: 2019
ISSN: 2081-237X
DOI: 10.5114/pedm.2019.89642